International standards of planning and design are of paramount importance for a modern laboratory facility. The higher the level and modernization of biological laboratory facilities and equipment, the higher the level, and the greater the significance of planning and design.
The construction of biological laboratory facilities in China is at a high-speed development stage. This requires the planning and design of biological laboratory facilities to propose both realistic and forward-looking architectural solutions and process design; requiring relevant managers to understand the basics of process design and development in modern biological laboratories.
The international advanced biological laboratory design concept mainly includes the following factors:
1. Maximize respect for the base environment
On the basis of a thorough analysis of the status quo of the base, in the concept of the project, the building is designed as the background of the environment, that is, the individual buildings are contained in the environment to express respect for the environment. This concept is also known as the concept of ecological architectural design.
Every laboratory has enough space to place instruments and equipment. Individual panels can also independently control their respective uses to ensure that they do not affect the relevant laboratory.
The laboratory should take into account the efficiency of the use of different types of work space, and divide the area to avoid waste of area and space.
A laboratory system based on a modular form of add-on structure and a reusable operating system enables the necessary shrinkage and expansion without sacrificing functionality or affecting the relevant laboratory.
The regional configuration of the laboratory needs to be divided according to its potential danger level. The location of the smoke shield, acid and flammable materials, and the space allocated for the biosafety bin will be placed in the higher hazard zone, ie at the back of the laboratory (away from the exit).
A certain amount of space and adequate waste passages will be used to create a second layer of protection for higher hazards. Each laboratory's low-risk zone will be used to arrange a variety of dry countertop activities, such as writing desks, computers and instruments. The wet countertop activity is placed in the middle danger zone.
Laboratory walkways and entrances and exits will provide easy access to action and provide appropriate access to relevant domestic codes.
3. Adapt to the development trend of biotechnology
In order to ensure the safety of laboratory personnel, prevention of environmental pollution is a prerequisite for conducting experimental research on pathogenic microorganisms. Because the laboratory is a high-risk work area that may cause the experimenter and the surrounding environment to be polluted, in the design, not only must meet the functional requirements, but also must follow the national standards and relevant industry professional standards, and draw reference to domestic and foreign biological laboratories. Design standards and related specifications to meet the requirements of general guidelines for the safety of microbiological and biomedical laboratories.
4. Promote the ability of scientific research
Modern laboratories emphasize the exchange and study between experimental personnel and the team spirit of laboratory personnel. Considering the characteristics of the activity of research activities, buildings must be able to adapt to changes in technology, equipment and skills, and promote the sharing and transfer of knowledge among researchers, thus forming an academic atmosphere of mutual encouragement and communication.
5. Reasonable use of space
Modern laboratory design generally adopts a unified column network and divides the unitized modules with different safety protection levels to suit different process requirements. This modular layout not only absorbs the advanced processes of CDC at home and abroad, but also enables the laboratory to meet the needs of future transformation.
6. Humanized treatment of indoor and outdoor environment
The indoor and outdoor environment is arranged with humanized design concept, providing efficient working place for laboratory staff and comfortable living space.
7. Attaches great importance to safety and security
Most of the laboratories in the project are secondary biosafety protection laboratories, which are suitable for the research work of microorganisms with moderate potential hazards to workers and the environment; some experimental areas are three-level biosafety protection laboratories, which are suitable for the main pass. Respiratory pathways lead to the study of pathogenic microorganisms and their toxins that cause serious or even lethal diseases. The prevention of microbial disasters, the design of biosafety secondary and biosafety tertiary laboratories is the focus.