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Renovation of clean room

Dec 15, 2020

When evaluating a space that may become a laboratory, the first thing to consider is how to make the existing building achieve the expected function according to the corresponding procedures and make it meet the requirements of the laboratory. Routine procedures required. Then, the laboratory procedures are classified, which can be divided into the following five types. Each set of procedures has its own concerns.

It is not used when designing a clean room, but a list of issues that need to be paid attention to when evaluating the suitability of a clean laboratory factory:

1. Process equipment

Required environmental conditions (cleanliness level, temperature, humidity);

Total area (operation area plus maintenance access);

Height and width (clearance of the entrance channel, and clearance of the installation of the elevator);

Weight (load that the existing building structure can carry);


2. External supply related to the process

The quality of water supplied to the building;

Laboratory exhaust emissions;

High purity water (RODI, WFI, distilled water);

Vacuum, CDA;

Gas and chemical substances (hazardous and high purity);

Process waste gas

Power supply (available voltage, reliability and quality);


3. Security measures

Hazardous materials (delivery, handling, storage, collection/processing of waste);

Separation of human flow and chemical/air flow;

The accessibility of the site and the building;

National safety requirements or regulations for hazardous materials;


4. The total space requirement

Space that can be modified or rented;

Laboratory space

Reserve space of the laboratory (equipment room, chemical and gas storage room);

Reserve space of clean room (dressing room, equipment room);

The mechanical space of the clean room (circulating air unit [RAU], refrigerator, humidifier, water supply, etc.);

The electrical space of the clean room (electric room, server room, IT cabinet, emergency generator);

Available roof space;


5. Budget and progress

Construction access restrictions;

Intervention activities;

The feasibility of the final time of construction.


Design requirements


Before starting the design, it is best to make a plan, first investigate the existing facilities, and merge the existing drawings (if the drawings have been prepared) whether they truly reflect the actual status quo.


In buildings, existing systems may become obstacles to design. This problem often occurs in HVAC main pipes, water and/or drain pipes, or other infrastructure.