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Several Questions Must Be Considered In Laboratory Design

Apr 08, 2018

1. Laboratory area and instrument placement


Before the construction of the laboratory, the position of the instrument should be determined according to the process of the laboratory's work, and the power supply of the instrument and the position of the water supply and drainage interface should be planned. The area required by each area is determined based on the number of instruments and their positions, and space is effectively used for the separation of laboratories. The instrument should be placed at the convenience of work while also considering the ground bearing problem. The instrument manufacturer should provide the instrument weight data and consult the construction engineer. The procurement bidding for equipment in this room has been completed before the design and construction of the laboratory. The layout of each instrument is precise and accurate. The power cord, network cable, and water supply and drainage pipe exposed on the ground are extremely short, which saves space for safety and beauty.


2. Laboratory power design


It is recommended that laboratories be equipped with high-power uninterruptible power supplies to protect all laboratory equipment. Each device is individually power-protected, difficult to maintain, and space-consuming. According to the situation of laboratory equipment, determine the uninterruptible power supply power and current parameters, it should be noted that the choice of uninterruptible power supply should reserve sufficient space for the development of the laboratory. It is recommended that the load power should be more than twice the total power of the existing instrument. The electrical plug can be designed on the wall or on the ground as required. The electrical plug on the ground should have a certain degree of waterproof. The electrical plug position should be close to the powered instrument, and the ground traces should be reduced to make the lab more tidy. Due to the uninterruptible power supply's heat dissipation and noise, the laboratory plans to set up an independent power supply room at the rear and install a dedicated air conditioner in the room.

3. Does the laboratory need to purify and purify the grade


Before the construction of the laboratory, the biosafety assessment shall be conducted according to the general guidelines for biosafety in microbiological and biomedical laboratories, the general requirements for laboratory biosafety in GB19489-2008, and the Biosafety Management Regulations for Laboratory of Pathogenic Microorganisms (Decree No. 424 of the State Council) to determine whether the laboratory needs Purification and purification levels. The assessment results of the laboratory suggest that the level of protection of automated laboratories should not be lower than the requirements of the BSL-2 laboratory. In the actual design, the laboratory's indicators fully comply with the requirements of BSL-2 laboratories, including clear identification, independent locker rooms, and independent warehouses. Equipped with eyewash, autoclave and emergency tools.


In addition, some of the requirements for BSL-3 laboratory construction were also referenced in the design. Floor height is not less than 2.6m, the net width of the channel in the laboratory is not less than 1.5m, and the door width is not less than 1m. At the same time, the height and width of the door should be convenient for instrument transportation in the laboratory. After the completion of the laboratory, the access control system, ventilation frequency, and temperature Some indicators such as humidity control reached the level of BSL-3 laboratory.


4. Laboratory water supply and drainage design


According to the amount of pure water and the grade required for full-load operation of all equipment, suitable water-making equipment shall be determined, and sufficient space shall be reserved for the water treatment capacity of the selected equipment. In this room design, the most noisy air pump (providing gas pressure for the automation assembly line) and the pure water treatment instrument are placed in the independent water machine room at the back of the central laboratory. The pure water meter leak-proof piping is directly connected to the laboratory drainage system and is located in the equipment room. The suction pump is set inside to facilitate handling of a certain degree of leakage. In addition, two ground recesses are also set on the axis of the laboratory instrument, and the drainage and drainage pipes are all laid underground.

5. Laboratory illumination and noise control design


According to the Biosafety Laboratory Building Technical Specifications, the BSL-2 laboratory illuminance should not be less than 300 lux and the noise should not exceed 68 dB. Before the interior decoration of the laboratory, the illumination requirements of the laboratory were put forward to the construction party. After the completion of the laboratory renovation, the illuminance was measured. The illuminance of the engine room was approximately 285-319 lux, and the illuminance of the core work area was approximately 375-384 lux, basically conforming to the BSL-2 laboratory. Construction standards. After taking measures such as independent hydropower, the environmental noise in the laboratory has been significantly reduced, especially in the relatively independent core work area, and the decibel number is basically the same as the general consulting room.


6. Laboratory temperature and humidity requirements


Refer to the instructions for use to calculate the temperature and humidity requirements of various equipment in automated laboratories. If no special equipment is required, clinical laboratory testing instruments require that the temperature be generally 18-30°C, humidity 20-80%, and the purification laboratory air conditioning system can fully meet the requirements. Laboratory temperature can be controlled at about 24°C and humidity 30%-45%.

7. Communication interface issues


The laboratory should reserve sufficient telephone interfaces, LAN interfaces, and Internet interfaces if necessary. Automated assembly line network connection is complicated. Before installation, it should be carefully discussed with the manufacturer's engineers to determine the exact location of the network interface. After the installation is completed, comb the connecting network cable to keep the lab clean and beautiful.


8. Completion of preparatory work in the laboratory


The establishment of an automated laboratory is a systematic project. In addition to the hardware construction, related preparations should be completed before the laboratory assembly line, such as the application and improvement of LIS, the connection between the LIS and the hospital information system (HIS), and barcodes. Printing and pasting standardization, two-way transmission of equipment, training of related personnel, etc.